I can speak from the Fightan N00BScrub's perspective and say that QuarterCircles are cool. They're pretty easy to pick up on. The only annoying ones are the ones that go Up, since that's usually Jump. I am very happy that they decided to implement a system that read for that in Skullgirls, so you don't try to do something fancy and end up jumping instead.
However, the V>^>V>>V^^VV>>V>Punch button combos that a lot of fighters I've seen like to use? That's assinine and I really hope we don't use something like that.